Full TRT (Testosterone Replacement Therapy) Diagnosis Test

Free testosterone represents the biologically active portion not bound to proteins. It directly affects energy, libido, muscle growth, and mood. Low free testosterone can cause symptoms even when total testosterone appears normal.

Men convert some testosterone into oestradiol. Small amounts are essential for bone, brain, and cardiovascular health. Elevated levels may cause water retention, mood changes, or gynecomastia, while low levels can cause joint pain, fatigue, and low libido on TRT.

LH regulates natural testosterone production. Low levels often indicate suppressed testicular function, common in men on TRT. High levels may suggest testicular under-response or fertility issues.

FSH controls sperm production. TRT typically lowers FSH levels, which may impact fertility. Measuring FSH gives insight into baseline reproductive function.

SHBG binds testosterone and controls how much is active. High SHBG reduces free testosterone; low SHBG increases androgen availability. This marker helps interpret symptoms when total testosterone alone is not clear.

FAI estimates how much testosterone is free and active by comparing testosterone to SHBG. Low FAI can indicate functional testosterone deficiency even when total levels look acceptable.

Prolactin influences reproductive function and libido. High levels may reduce testosterone, impair sexual function, or cause fatigue. It is important to rule out elevated prolactin before or during TRT.

PSA is produced by the prostate gland. Monitoring PSA helps detect prostate inflammation, enlargement, or early prostate disease. It is essential for safety when assessing suitability for TRT.

Haemoglobin carries oxygen around the body. TRT can increase haemoglobin; excessively high levels may raise clotting risk. Monitoring ensures safe testosterone therapy management.

Shows the percentage of blood made up of red blood cells. TRT may elevate haematocrit, and high levels can thicken the blood. Keeping it within range is key for long-term cardiovascular safety.

Measures the number of red blood cells in circulation. TRT often increases RBC production, which can improve energy but must be monitored to avoid excessive elevation.

Shows the average size of your red blood cells. Abnormal results may indicate B12, folate or iron imbalance, which can impact energy levels and oxygen delivery.

Measures how much haemoglobin each red cell contains. Low levels suggest iron-related issues; high levels may relate to dehydration or less common blood conditions.

Indicates overall immune system activity. Abnormal levels may reflect infection, inflammation, or immune suppression. Important for understanding general health during TRT.

A major type of white blood cell that fights bacterial infection. High levels indicate inflammation or infection; low levels may reduce immune defence.

Support viral immunity and long-term immune memory. Abnormal results may reflect infection, stress response, or immune imbalance.

White blood cells involved in clearing debris and chronic inflammation. Raised levels may suggest prolonged inflammation; low levels may reflect bone marrow fatigue.

Cells involved in allergic reactions and parasitic defence. High levels often reflect allergies, asthma, or inflammatory responses.

The least common white blood cell type, linked to allergic and inflammatory responses. Elevated levels may indicate ongoing histamine or immune activity.

Platelets help with blood clotting. TRT can sometimes affect platelet behaviour, so monitoring is important. High or low levels may signal inflammation, nutrient issues, or bleeding risk.

A breakdown product of red blood cells processed by the liver. Elevated levels may indicate liver stress, increased red cell turnover, or bile duct issues. Mild elevations can be harmless in some individuals.

An enzyme linked to liver and bone health. High levels may indicate bile duct irritation or increased bone turnover. Low levels can relate to nutritional deficiencies.

A key liver enzyme used to assess liver cell integrity. Elevated ALT may reflect fatty liver, alcohol effects, medication impact, or general liver stress.

A liver enzyme also found in muscles. High levels can indicate liver inflammation or muscle injury. Interpreted alongside ALT for a fuller picture.

A sensitive marker for liver stress, alcohol use, and toxin exposure. High levels may indicate early liver irritation before other markers rise.

A protein made by the liver that helps maintain fluid balance and transport hormones. Low levels may indicate inflammation, liver dysfunction or nutritional issues.

Measures the overall protein levels in your blood, including albumin and globulins. Abnormal levels may indicate liver disease, immune activation, or hydration issues.

Proteins involved in immunity and inflammation. High levels may signal chronic inflammation or immune activity; low levels may reflect nutritional or immune imbalance.

A waste product filtered by the kidneys. High levels can indicate dehydration, high protein intake, or reduced kidney function. Low levels may suggest liver or nutrition-related issues.

A marker of kidney filtration and muscle metabolism. Elevated levels may indicate reduced kidney function or higher muscle mass. Used to calculate eGFR.

Shows how effectively your kidneys filter waste. Lower values indicate reduced kidney function. Essential for monitoring kidney safety before and during TRT.

Controls thyroid hormone release. High levels suggest an underactive thyroid; low levels indicate possible overactivity. Thyroid imbalance can affect energy, mood, and testosterone levels.

A key thyroid hormone involved in metabolism. Low FT4 suggests an underactive thyroid, while high levels indicate excess activity. Interpreted together with TSH.

Shows the overall level of cholesterol in your blood. High levels may increase cardiovascular risk. Important when monitoring TRT, as hormones impact lipid balance.

Fat molecules used for energy. High levels may signal insulin resistance, metabolic issues, or poor dietary balance. Important for cardiovascular risk assessment.

Important for immunity, skin health, hormones, and wound healing. Low levels may contribute to hair loss, low libido, and reduced immunity.

The “bad” cholesterol that can contribute to plaque build-up in arteries. High LDL is associated with increased cardiovascular risk.

Shows the balance between total cholesterol and protective HDL. A lower ratio is linked with lower cardiovascular risk; higher ratios warrant attention.

Includes all potentially harmful cholesterol particles. A strong predictor of heart disease risk and often more reliable than LDL alone.

Your body’s iron storage protein. Low levels may contribute to fatigue, reduced performance, and poor recovery. High levels may indicate inflammation or iron overload.

Reflects your average blood glucose over the last 2–3 months. High levels suggest impaired glucose control, insulin resistance, or diabetes risk. Important because TRT can influence metabolic health.

Shows how much capacity your blood has to transport iron. High TIBC often suggests iron deficiency. Low TIBC may signal inflammation or iron overload.

Indicates how much of the iron-transport protein (transferrin) is actually carrying iron. Low levels suggest deficiency; high levels may indicate excess iron.

Your body’s iron storage protein. Low ferritin is one of the most common causes of fatigue. High ferritin may signal inflammation or iron overload conditions.

The oxygen-carrying protein in red blood cells. Low levels can indicate anaemia, causing fatigue and breathlessness. High levels may suggest dehydration or increased oxygen demand.

Shows the proportion of blood made up of red blood cells. Low levels often indicate anaemia; high levels may suggest dehydration or increased red cell production.

Measures the number of red blood cells in circulation. Abnormal levels may indicate anaemia, nutrient deficiencies, or bone marrow changes.

Shows the average size of your red blood cells. High MCV may indicate B12 or folate deficiency; low MCV is common in iron deficiency.

Measures how much haemoglobin is in each red blood cell. Low levels are often seen in iron deficiency; high levels may relate to B12 or folate status.

Reflects immune system activity. High levels may indicate infection or inflammation; low levels may reflect immune suppression or nutrient deficiency.

Shows the number of platelets involved in clotting. High or low levels may indicate inflammation, infection, or bone marrow changes. Important for bleeding and clotting health.